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If you have a project that needs a bit more than 3.3, 5 or 12 volts have a look at this Home Made 250 kV High Voltage DC Power Supply! Of course this isn’t your typical supply for the Arduino project sitting on the corner of your bench. “The Cockroft-Walton multiplier uses a cascaded series of diodes and capacitors to generate a high voltage DC potential from an AC input through a circuit topology that uses diodes to charge capacitors in parallel and discharge them in series. The output polarity of the Cockroft-Walton multiplier depends on the way in which its diodes are oriented, so the output polarity (referenced to ground) of a high-voltage DC power supply is usually set during the design.”
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One thing to note is that this supply can pack a deadly punch so be very careful if you intend to do some tinkering on your own. 
February 10th, 2012
X-Ray machine anyone?
February 10th, 2012
That would be nice for setting up a railgun. Must be what the US Navy is using on their new toy..
February 12th, 2012
@Nick: Railguns rely on high current (thousands of amps or more) and moderate voltages (~2000 – 4000V). This thing can’t produce the current necessary for a rail gun. But as I said before, this would make an great x-ray power supply or a supply for a home made electron microscope. Or to do heinous things to your cat…
February 12th, 2012
[...] 250 kV Home Made High Voltage DC Power Supply [...]
February 14th, 2012
“… John Douglas Cockcroft and Ernest Thomas Sinton Walton, who in 1932 used this circuit design to power their particle accelerator, performing the first artificial nuclear disintegration in history. …” http://en.wikipedia.org/wiki/Cockcroft%E2%80%93Walton_generator
Ouch.
June 25th, 2012
It is one thing to create HV DC but I have sound very difficult to switch reliably
Has any one got a suggestion for switching 2000v DC from a capacitor on and off in micro seconds with out needing to drop the voltage to zero?
Tried vacuum reeds but forward / reverse rush kills them very quickly.